The Five Times Sit-to-Stand Test: safety and reliability with older intensive care unit patients at discharge

ABSTRACT Objective: Assess the Five Times Sit-to-Stand Test safety and clinimetric properties in older patients hospitalized in an intensive care unit. Methods: Test safety was assessed according to the incidence of adverse events and through hemodynamic and respiratory data. Additionally, reliability properties were investigated using the intraclass correlation coefficients, standard error of measurement, standard error percentage change, Altman-Bland plot and a survival agreement plot. Results: The overall suitability of the Five Times Sit-to-Stand Test was found to be low, with 29.8% meeting the inclusion criteria. Only 44% of the hospitalized patients who met the inclusion criteria performed the test, with no need for discontinuation in any patient. Heart rate (79.7 ± 10.2bpm/86.6 ± 9.7bpm; p = 0.001) and systolic blood pressure (118 ± 21.4mmHg/129 ± 21.5mmHg; p = 0.031) were the only variables that presented a significant statistical increase, with no evidence of exacerbated response to the test. Additionally, no adverse events were reported from participating and both test-retest and interrater reliability were high (intraclass correlation coefficient ≥ 0.99). Conclusion: The Five Times Sit-to-Stand Test was proven to be safe and to have excellent reliability. Its clinical use, however, may be restricted to high-functioning older adults in hospital settings.

【摘要】研究目的：评估五次坐立试验（Five Times Sit-to-Stand Test）在重症监护病房住院老年患者中的安全性与临床测量学特性。研究方法：本研究通过不良事件发生率、血流动力学与呼吸相关数据评估该试验的安全性；此外，采用组内相关系数、测量标准误、百分比变化标准误、Altman-Bland图以及一致性生存图对其信度属性进行考察。研究结果：五次坐立试验的整体适配率较低，仅29.8%的受试者符合纳入标准。在符合纳入标准的住院患者中，仅有44%完成了试验，且无患者因不耐受终止试验。心率（79.7±10.2次/分钟/86.6±9.7次/分钟；p=0.001）与收缩压（118±21.4mmHg/129±21.5mmHg；p=0.031）是仅有的两项出现显著统计学升高的指标，未观察到试验诱发的过度生理反应。此外，参与试验未报告任何不良事件，且重测信度与评定者间信度均较高（组内相关系数≥0.99）。研究结论：五次坐立试验被证实安全性良好且具备优异的信度。但在临床场景中，其应用可能仅局限于住院的高功能老年患者。