MOESM4 of De novo variants in exomes of congenital heart disease patients identify risk genes and pathways

Additional file 4: Enrichment analyses in validation set: Table S10. De novo mutations in the filtered validation dataset, Table S11. IPA canonical pathways among 30 genes in validation dataset, Table S12. InnateDB pathway analysis among 30 genes in validation dataset, Table S13. InnateDB GO analysis among 30 genes in validation dataset, Table S14a. IPA Networks among 30 genes in validation dataset, Table S14b. NetworkAnalyst PPI Network among 30 genes in validation dataset, Table S15. InnateDB GO analysis among 30 random genes from unfiltered validation dataset.

附加文件4：验证集富集分析相关内容，包含如下表格：表S10为过滤后验证数据集中的新生突变；表S11为验证数据集30个基因的Ingenuity通路分析（Ingenuity Pathway Analysis，IPA）经典通路富集结果；表S12为验证数据集30个基因的InnateDB通路分析结果；表S13为验证数据集30个基因的InnateDB基因本体（Gene Ontology，GO）富集分析结果；表S14a为验证数据集30个基因的Ingenuity通路分析（IPA）网络分析结果；表S14b为验证数据集30个基因的NetworkAnalyst蛋白质-蛋白质相互作用（Protein-Protein Interaction，PPI）网络分析结果；表S15为从未过滤验证数据集中随机选取的30个基因的InnateDB基因本体（GO）富集分析结果。