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Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation

ChEBI2016-06-28 更新2026-07-12 收录

线粒体应激反应

RNA加工与翻译调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-75247 数据链接链接失效反馈

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资源简介：

Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation

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创建时间：

2016-06-28

细胞信号传导

线粒体应激反应

Mitochondria control eukaryotic cell fate by producing the energy needed to support life and the signals required to execute programmed cell death. The biochemical milieu is known to affect mitochondr

NIAID Data Ecosystem40

Amino acid alignments used for phylogenetic analysis of MISTR sequences in Fig 7 and S6 and S7 Figs. MISTR, MItochondrial STress Response.

系统发育分析

线粒体应激反应

(TXT)

NIAID Data Ecosystem30

Integrated stress response couples mitochondria protein translation with oxidative stress control

缺血性卒中机制

线粒体应激反应

Under stress conditions, cells elicit integrated stress response (ISR) to cope with intracellular and extracellular disturbances. However, its role in ischemic heart disease remains to be elucidated.

NIAID Data Ecosystem30

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

衰老分子机制

线粒体应激反应

Across eukaryotic species, mild mitochondrial stress can have beneficial effects on the lifespan of organisms. Mitochondrial dysfunction activates an unfolded protein response (UPRmt), a stress signal

NIAID Data Ecosystem30

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress [ChIP-seq]. The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress [ChIP-seq]

线粒体应激反应

表观遗传调控

Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPRmt). However, how different layers of UPRmt regulators are o

NIAID Data Ecosystem30

Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation

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