Transcriptome analysis of paired luminal breast tumor and para-carcinoma tissues

With stringent filtering criteria (fold change>2, p<0.001 and False Discovery Rate (FDR) <0.01), we identified 133 lncRNAs and 370 mRNAs that were the most highly differentially expressed. Of all the lncRNAs, 61 were upregulated, and 72 were downregulated. Twenty one paired luminal breast tumor (ER+) and para-carcinoma RNA samples extracted from fresh frozen tissues were analyzed using the Affymetrix Human Transcriptome 2.0 Arrays. Array data was processed by Partak genomic suite software.