Effect of HFD exposure on hepatic transcriptome on Wild Type mice (WT), hepatocyte-specific PPARα knockout mice (LKO) and whole body PPARα knockout mice (KO).. Effect of HFD exposure on hepatic transcriptome on Wild Type mice (WT), hepatocyte-specific PPARα knockout mice (LKO) and whole body PPARα knockout mice (KO).

Adult (12 weeks old) WT, LKO and KO male mice from C57Bl6J were either treated with a control diet (CTRL) or an High Fat Diet (HFD) during 12 weeks prior to liver gene expression analysis Overall design: 8 mice per group (CTRL and HFD) and per genotype (WT, LKO, KO).