Source data_An EDP-EBP interaction inhibitor reverses IPF

NIAID Data Ecosystem2026-05-01 收录

纤维化治疗靶点

药物靶点相互作用

数据链接：

https://figshare.com/articles/dataset/Source_data_An_EDP-EBP_interaction_inhibitor_reverses_IPF/24418927 数据链接链接失效反馈

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资源简介：

Source data-An EDP-EBP interaction inhibitor reverses pulmonary fibrosis.

创建时间：

2023-10-23

ALK in complex with ceritinib with in-silico mutated residues

药物靶点相互作用

耐药性机制

PyMol session file (.pse) files of the structure of ALK in complex with ceritinib (original PDB accession 4MKC) with in-silico mutated residues as reported in figure 4. Computational mutagenesi

Figshare2025-01-22 更新30

Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole

蛋白质晶体学

药物靶点相互作用

Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole Descriptor: 4-(4-CHLOROPHENYL)IMIDAZOLE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cy

Protein Data Bank Japan2023-09-06 更新20

Crystal structure of TNKS2 in complex with 2-(2,4-dichlorophenyl)-1- methyl-1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one

蛋白质晶体学

药物靶点相互作用

Crystal structure of TNKS2 in complex with 2-(2,4-dichlorophenyl)-1- methyl-1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one Descriptor: (2R)-2-(2,4-dichlorophenyl)-1-methyl-2,3-dihydropyrido[2,3-d]pyrimidin-

Protein Data Bank Japan2024-01-10 更新10

Crystal Structure of FGFR1 (C488A, C584S) in complex with AZD4547 (N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE)

结构生物学

药物靶点相互作用

Crystal Structure of FGFR1 (C488A, C584S) in complex with AZD4547 (N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE) Descriptor: Fibroblast growth f

Protein Data Bank Japan2023-09-20 更新20

Data_Sheet_1_Inhibition of the SET8 Pathway Ameliorates Lung Fibrosis Even Through Fibroblast Dedifferentiation.pdf

纤维化治疗靶点

表观遗传调控

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown etiopathogenesis. The activation of extracellular matrix (ECM)-producing myofibroblasts plays a key role in fibrotic tissue remod

NIAID Data Ecosystem20

Source data_An EDP-EBP interaction inhibitor reverses IPF

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