Heat shock protein gp96 induces Foxp3 expression in Regulatory T Cells via interaction with TLRs for treatment of Auto-immune Diseases [FFoxp3-GFP-hCre]
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
Upregulate and stabilize Foxp3 expression in Treg are essential for manipulating Treg cell function and immune homeostasis. Here, we examined the potential role and mechanism of gp96 protein in regulating FoxP3 transcription and Treg activation in vivo. Overall design: We analyzed gene-expression profiles of FoxP3-GFP+ Tregs from Foxp3-GFP-hCre mice immunized with gp96 and pbs.
创建时间：
2021-12-16
