Investigation of alteration in gene expression during oxidative stress in ∆wee1S. pombe cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE173744
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Treating wild-type S. pombe cells and ∆wee1 mutant with 20mM H2O2, we observed that aberrant Cdc2 activity, as in case of ∆wee1 cells can lead to major changes in the Spc1 dependent global transcriptional response to oxidative stress. Differential gene expression studies were carried out using Next Generation Sequencing , following 20mM H2O2 treatment in a Wee1 ldeletion mutant w.r.t untreated cells. Two biological replciates per condition and genotype.
创建时间：
2021-05-04
