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Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to TP-238

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to TP-238 Descriptor: 1,2-ETHANEDIOL, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF Authors: Chan, A, Schonbrunn, E. Deposit date: 2020-10-09 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.54 Å) Cite: New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development Organic & Biomolecular Chemistry, 18(27), 2020
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2020-10-09
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