Expression profile of Ras, MEK and ERK inhibited 16HBE bronchial epithelial cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63229
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资源简介：
To identify Ras, MEK and ERK target genes which regulate tight junction formation in 16HBE bronchial epithelial cells 16HBE cells were stably infected with pQCXIP retroviral vector, or pQCXIP expressing dominant negative Ras (DN Ras). pQCXIP cells were treated with DMSO (control), 500nM GSK1120212 (MEK inhibitor) or 1uM SCH772984 (ERK inhibitor) for 4 days, then total RNA was extracted. 4 samples were harvested per experiment: pQCXIP/DMSO, pQCXIP/MEKi, pQCXIP/ERKi, pQCXIP.DN Ras. This was repeated in 3 independent experiments. Gene expression was compared to the pQCXIP/DMSO control.
创建时间：
2018-12-02
