Effect of video-assisted patient education on compliance with therapy, quality of life, psychomorbidity, and cost of illness in irritable bowel syndrome

<b>Objective:</b> Patient education is important in irritable bowel syndrome (IBS), but its effects on outcomes have not been studied extensively. <b>Methods</b>: Patients were enrolled and prospectively divided into an interventional and usual care group. Both received standard of care, but the former additionally received video-assisted patient education. Self-administered questionnaires IBS-quality of life (QOL), Beck Anxiety-Depression Inventory II (BAI, BDI), and Hospital Anxiety and Depression Scale (HADS) were administered at baseline, 3 months, and 6 months. Compliance was defined as drug intake of &gt;80% of the prescribed dose. COI included prospective, prevalence-based, societal perspective. <b>Results</b>: Of the 107 patients included, 84 [78.5%; male = 66 (78.57%); median age = 44 (range 20–77 years)] completed the follow up. While the median (inter-quartile range; IQR) QOL scores decreased significantly in both the groups (<i>p</i> p p <b>Conclusion</b>: Video-assisted patient education should be a part of the treatment of IBS since it improves the QOL and depression scores.

**研究目的**：肠易激综合征（irritable bowel syndrome, IBS）患者教育对疾病管理意义重大，但目前其对临床结局的影响尚未得到广泛研究。**研究方法**：本研究纳入患者并前瞻性分为干预组与常规护理组。两组均接受标准诊疗护理，干预组额外辅以视频形式的患者教育。分别于基线、3个月及6个月时，采用自填式问卷评估患者的IBS生活质量（quality of life, QOL）、贝克焦虑抑郁量表II（Beck Anxiety-Depression Inventory II, BAI、BDI）以及医院焦虑抑郁量表（Hospital Anxiety and Depression Scale, HADS）。依从性定义为患者实际服药剂量达到处方剂量的80%以上。疾病经济负担（cost of illness, COI）评估采用基于患病率的前瞻性社会视角法。**研究结果**：本研究共纳入107例患者，其中84例[78.5%；男性66例（78.57%）；中位年龄44岁（范围20~77岁）]完成全部随访。两组患者的中位（四分位间距，IQR）生活质量评分均显著降低（*p* *p* *p*）。**研究结论**：视频辅助患者教育应作为肠易激综合征治疗的常规组成部分，因其可有效改善患者的生活质量与抑郁评分。