Additional file 2 of Mendelian randomisation to uncover causal associations between conformation, metabolism, and production as potential exposure to reproduction in German Holstein dairy cattle

Additional file 2. Tables S3 to S4. GWAS results. Results for genome-wide association studies for 12 exposure (complex of conformation, metabolism and production) and 13 outcome traits (all reproduction) surpassing the genome-wide significance threshold after Bonferroni-correction (p = 1.11 * 10-6 [(0.05/44,994), - log10 (P) ≈ 5.95]. For each SNP per trait surpassing the significance threshold, the chromosome (Chr), marker localisation in base pairs (bp) and marker name (SNP) are given. Further, the respective alleles and frequencies (A1, A2, Freq), the signed Z-scores (Zscore) and the p-value (p).

补充材料2：表S3至表S4。全基因组关联分析（Genome-Wide Association Study, GWAS）结果。针对12个暴露性状（构象、代谢与生产复合性状）以及13个结局性状（均为繁殖相关性状）的全基因组关联分析结果，经邦弗朗尼校正（Bonferroni-correction）后达到全基因组显著性阈值（p=1.11×10⁻⁶，对应0.05/44994，-log₁₀(P)≈5.95）。对于每个达到显著性阈值的性状对应的单核苷酸多态性（Single Nucleotide Polymorphism, SNP），将提供其所在染色体（Chr）、标记的碱基对（bp）定位信息以及标记名称（SNP）。此外还将提供对应的等位基因及频率（A1、A2、Freq）、带符号Z值（Zscore）以及p值（p）。