Additional file 2 of Relationship between autism and brain cortex surface area: genetic correlation and a two-sample Mendelian randomization study

Supplementary Material 2: Table S1. Information of studies on SA alternation between ASD and controls. Table S2. Descriptions of study cohorts from ENIGMA3 Cortical GWAS Data. Table S3. The results of LDSC for each cortical SA. Table S4. The results of HESS for each cortical SA. Table S5. 45 index SNPs represented genetically predicted ASD. Table S6. Results of MR-presso. Table S7. Details for Mendelian randomization studies with tightened instrument variables selection. Table S8. Results of IVW through FDR correction. Table S9. Results of MR-Egger intercept test and Cochran’s Q test. Table S10. Results of Mendelian randomization with the cortical surface area as the exposure

补充材料2：表S1。自闭症谱系障碍（Autism Spectrum Disorder, ASD）与对照组间皮层表面积（Cortical Surface Area, SA）相关研究的基本信息。表S2。ENIGMA3皮层全基因组关联研究（Genome-Wide Association Study, GWAS）数据对应的研究队列概况。表S3。各皮层表面积的连锁不平衡得分回归（Linkage Disequilibrium Score Regression, LDSC）分析结果。表S4。各皮层表面积的HESS分析结果。表S5。用于遗传预测自闭症谱系障碍的45个索引单核苷酸多态性（Single Nucleotide Polymorphism, SNP）位点。表S6。MR-PRESSO分析结果。表S7。采用严格工具变量筛选的孟德尔随机化（Mendelian Randomization, MR）研究详细信息。表S8。经错误发现率（False Discovery Rate, FDR）校正后的逆方差加权（Inverse Variance Weighted, IVW）分析结果。表S9。MR-Egger截距检验与科克伦Q检验（Cochran's Q test）结果。表S10。以皮层表面积作为暴露因素的孟德尔随机化分析结果。