Gene expression profile in mouse skin. Gene expression profile in mouse skin

Auto-reactive T cells attack self-tissues, leading to severe tissue damage, such as inflamed skin lesion. However, the key molecule involved in autoimmune skin lesion is unknown. By using gene expression microarray analysis, we aimed to identify the key molecule as a mediator of the autoimmune skin lesion, which could be a potential target for therapy. Overall design: Three WT samples, three knock-in samples.