Glycogenesis

Glycogenesis is the process of glycogen synthesis. Glycogen is a polymer of glucose residues that is linked by α-1,4 and α-1,6 glycosidic bonds. Glycogenin initiates the process by self glycosylation of a short 8–12 glucose oligosaccharide primer. Glycogen synthase (GYS) utilises UDP-glucose as the glucosyl donor and elongates the glucose oligossacharide primer. Glycogen branching enzyme 1 (GBE1) generates α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer.