High-sucrose diets disrupt gut micriobiota

Sucrose, a common sweeter, is frequently added to drink and food, and excess intake of sucrose is really harmful to our health. This study aimed to reveal the potential mechanisms of high-sucrose induced metabolic dysfunction. Sixty mice were divided into two groups, respectively, the normal group (Nor group) and high-sucrose group (HS group). 16S rDNA was used to analyzed the dynamic changes of gut microbiota in colon contents of young mice, middle age mice and old mice.