Additional file 7: Table S2. of Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells

Proteins significantly regulated upon TRAP perturbation in any of the phosphoproteomics or proteomics analyses (TRAP3high vs ctrl, phospho and standard proteomics analyses; TRAP sh2 or sh3 + 4 vs scrambled shRNA, standard proteomics analysis). The column “Enriched GO term” specifies whether the protein belong to any of the GO terms that were found to be enriched in the list of regulated proteins. The column “Protein class” describes to which of the examined protein class a protein belongs to. Examined proteins classes include protein kinases, protein phosphatases, ubiquitin and UBL system enzymes and transcription factors. (XLSX 79 kb)

本数据集收录经TRAP扰动后，在任一磷酸化蛋白质组学或常规蛋白质组学分析中呈现显著差异表达的蛋白质，相关分析分组包括：TRAP3高表达组（TRAP3high）与对照组（ctrl）的磷酸化蛋白质组学及常规蛋白质组学分析；TRAP sh2、sh3+4组与乱序短发夹RNA（scrambled shRNA）对照组的常规蛋白质组学分析。其中"富集GO条目（Enriched GO term）"列用于标注该蛋白质是否属于在差异表达蛋白质列表中被鉴定出富集的任一基因本体（GO）条目；"蛋白质类别（Protein class）"列用于说明该蛋白质归属于何种已纳入本次分析的蛋白质类别。本次分析涵盖的蛋白质类别包括蛋白激酶、蛋白磷酸酶、泛素及泛素样（UBL）系统酶与转录因子。（XLSX 79 KB）