Data set for the paper "Effects of latent toxoplasmosis on mental health"

Data are described in the paper "<b>Effects of latent toxoplasmosis on mental health"</b><b>Abstract</b>Infection by the parasite <i>Toxoplasma</i>, which affects about 33% of world population, is associated with increased risk of several mental health disorders, especially with schizophrenia. It is unknown whether schizophrenia is associated with this infection the most strongly, or whether this association has just been the most intensively studied for historical reasons. We used the data from 6,367 subjects tested for toxoplasmosis, who took part in an internet survey, for searching in the associations of these infections with 24 mental health disorders and other indices of impaired mental health. The typical symptom associated with toxoplasmosis was anxiety, and the typical toxoplasmosis-associated disorders were autism (OR=4.78), schizophrenia (OR=3.34), attention deficit hyperactivity disorder (OR=2.50), obsessive compulsive disorder (OR=1.86), antisocial personality disorder (OR=1.63), learning disabilities (OR=1.59), and anxiety disorder (OR=1.48). Based on our data we can conclude that Toxoplasmosis probably plays a substantial role in the etiopathogenesis of mental health disorders and its association with schizophrenia is the second strongest association, after autism.<b></b>

本研究数据源自论文《隐性弓形虫感染对心理健康的影响》（Effects of latent toxoplasmosis on mental health），其摘要内容如下：弓形虫（Toxoplasma）感染影响全球约33%的人口，与多种精神健康障碍的发病风险升高存在显著关联，其中尤以精神分裂症（Schizophrenia）最为突出。目前学界尚未明确，精神分裂症与该感染的关联是否为强度最高的关联，亦或是该关联因历史原因被研究得最为深入。本研究纳入6367名参与互联网调查并接受弓形虫感染检测的受试者，通过其数据探究该感染与24种精神健康障碍及其他心理健康受损指标的关联。研究结果显示，与弓形虫感染相关的典型症状为焦虑，典型的相关精神障碍包括：孤独症（Autism），比值比（Odds Ratio，OR）=4.78；精神分裂症（Schizophrenia），OR=3.34；注意缺陷多动障碍（Attention Deficit Hyperactivity Disorder），OR=2.50；强迫症（Obsessive Compulsive Disorder），OR=1.86；反社会人格障碍，OR=1.63；学习障碍，OR=1.59；以及焦虑障碍，OR=1.48。基于本研究数据，我们可得出结论：弓形虫感染可能在精神健康障碍的发病机制中发挥重要作用，其与精神分裂症的关联强度位列第二，仅次于孤独症。