Crystal structure of human KDM4A in complex with compound 53a
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Crystal structure of human KDM4A in complex with compound 53a Descriptor: 8-[4-[2-[4-[(4-chlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Le Bihan, Y.-V, Westwood, I.M, van Montfort, R.L.M. Deposit date: 2015-12-02 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.5 Å) Cite: 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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2015-12-02
