Metabolic evaluation in overweight and obese cats and association with blood pressure

ABSTRACT: Obesity has been increasing in cats andis associated with metabolic and cardiovascular diseases. The association of these alterations can trigger the onset of metabolic syndrome (MS). Therefore, this study aimed to analyze the serum levels of glucose, fructosamine, cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein (VLDL), andalanine aminotransferase of cats and to identify the possibility of MS,as well as to evaluate changes in arterial pressure. Thirty-seven cats were classified by ECC and morphometric measurements, namely, 15 obese, 12 overweight, and 10 controls. Nocat manifested MS. Only VLDL had a statistically significant difference (P<0.05) between groups. Therefore, obesity may not be associated with arterial hypertension, and more studies are needed to evaluate the metabolic alterations in overweight and obese cats.

摘要：猫群的肥胖患病率呈逐年上升趋势，且与代谢性疾病及心血管疾病密切相关。此类机体代谢与生理改变可能诱发代谢综合征（metabolic syndrome, MS）的发生。本研究旨在检测猫的血清葡萄糖、果糖胺、胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白（very low-density lipoprotein, VLDL）以及丙氨酸氨基转移酶水平，以探究代谢综合征的发病可能性，同时评估受试猫的动脉血压变化情况。研究共纳入37只猫，通过ECC评分与体尺测量指标将其分为3组：肥胖组15只、超重组12只、对照组10只。所有受试猫均未表现出代谢综合征相关症状。仅极低密度脂蛋白（VLDL）在各组间存在统计学差异（P<0.05）。由此表明，猫的肥胖可能与动脉高血压无显著关联，后续仍需开展更多研究以全面评估超重及肥胖猫的代谢异常情况。