Pilot fMRI of breath-hold in OSA

Pilot fMRI project on neuroimaging of two obstructive sleep apnea (OSA) and two control subjects. The purpose is to establish validity and feasibility of performing maximal inspiratory apnea during fMRI scanning as a means to test neural control of autonomic function. The data also serve as a test set for assessing fMRI signals during physiologic challenges.

本试点功能磁共振成像（fMRI）研究项目以2名阻塞性睡眠呼吸暂停（OSA）患者及2名健康对照受试者为研究对象，开展神经影像学相关研究。本研究的核心目标在于验证在功能磁共振成像扫描过程中实施最大吸气性呼吸暂停任务的有效性与可行性，以此作为测试自主神经功能神经调控机制的实验手段。本数据集同时可作为评估生理应激状态下功能磁共振成像信号的测试集。