Emergence and Rise of E Gene Mutations in SARS-CoV-2: A Longitudinal Study of 9.3 Million Genomes (2020 to 2025)

This dataset provides a comprehensive analysis of mutations in the SARS-CoV-2 Envelope (E) gene, focusing on their emergence and frequency changes before and after the global rollout of COVID-19 vaccines (post-2022). The dataset includes: All mutation sets observed in the E gene. Mutations that newly emerged post-2022. Mutations that dramatically increased in frequency post-2022. The data is derived from over 9 million high-quality SARS-CoV-2 genome sequences. This resource is valuable for studying viral evolution, vaccine-driven selection pressures, and potential functional impacts of E gene mutations.