The positive preventive effect of LIPUS on cognitive decline in hind limb unloaded mice is achieved by regulating gut microbiota

Weightlessness usually causes disruption of the gut microbiota and impairs cognitive function. There is a close connection between gut microbiota and neurological diseases. Although low intensity pulsed ultrasound (LIPUS) has a beneficial effect on reducing intestinal inflammation, further research is needed to determine whether abdominal LIPUS stimulation can have a positive impact on weightlessness induced cognitive decline by reducing intestinal dysfunction.