Comparison of virus and disease severity of the main cohort considering the virus as single pathogen or as co-infection in the sample.

Different statistical models were considered to study the bivariate association between the variables depending on the dependent variable. A binary logistic model was used for the binary variables oxygen needed and respiratory support needed, and a negative binomial regression model for counted data (hospital stay length). Data are presented as OR (confidence interval 95%) and the level of statistical significance was set at 0.05.