Combinatorial Synthesis of Fused Tetracyclic Heterocycles Containing [1,6]Naphthyridine Derivatives under Catalyst Free Conditions
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https://figshare.com/articles/dataset/Combinatorial_Synthesis_of_Fused_Tetracyclic_Heterocycles_Containing_1_6_Naphthyridine_Derivatives_under_Catalyst_Free_Conditions/2415829
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资源简介：
A three-component
reaction between an aromatic aldehyde, an amine,
and tert-butyl 2,4-dioxopiperidine-1-carboxylate
in EtOH at refluxing temperature gave fused tetracyclic heterocycles
in high yields. The amines include 1H-indazol-5-amine,
1H-indazol-6-amine, 1H-indol-5-amine,
and 1H-benzo[d]imidazol-5-amine,
giving 11-aryl-3H-indazolo[5,4-b][1,6] naphthyridine, 11-aryl-1H-indazolo[6,7-b][1,6]naphthyridine, 11-aryl-3H-indolo[5,4-b][1,6]naph-thyridine, and 11-aryl-3H-imidazo[4′,5′:3,4]benzo[1,2-b][1,6]naphthyridine derivatives, respectively.
创建时间：
2016-02-19
