tRNA-binding repertoire of human ABH8. Homo sapiens cultivar:HEK293
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA676158
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资源简介:
The ultimate step of tRNA wobble uridine modification 5-methoxycarbonylmethyluridine (mcm5U) and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) is generated by ABH8. Four tRNAs have been presented to bear the ABH8-catalyzed modification. In this study, we provide a global view on the binding repertoire of human ABH8 by HITS-CLIP and RIP-seq of ABH8-bound RNA. We demonstrate tRNA-Lys-UUU as a target that has not been previously identified in humans.
创建时间:
2020-11-11



