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G13D mutant of KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation crystallized in sodium potassium phosphate buffer

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Protein Data Bank Japan2024-09-11 更新2026-03-28 收录
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G13D mutant of KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation crystallized in sodium potassium phosphate buffer Descriptor: GTPase KRas, N-terminally processed, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Moche, M, Jungholm, O, Strandback, E, Ampah-Korsah, H, Nyman, T, Orwar, O. Deposit date: 2023-03-03 Release date: 2024-06-12 Last modified: 2024-09-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody. Sci Rep, 14, 2024
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2023-03-03
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