Local refinement of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)

Protein Data Bank Japan2025-05-28 更新2026-06-30 收录

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Local refinement of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM) Descriptor: 2,5-dimethoxy-N,N-dimethyl-4-{2-[({2-[(prop-2-yn-1-yl)oxy]phenyl}methyl)amino]ethyl}aniline, 5-hydroxytryptamine receptor 2A Authors: Gumpper, R.H, Fay, J.F, Roth, B.L. Deposit date: 2024-02-24 Release date: 2025-04-02 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: The structural diversity of psychedelic drug actions revealed. Nat Commun, 16, 2025

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2024-02-24