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Studies on the Synthesis of Furanosteroids. I. Viridin Models

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https://figshare.com/articles/dataset/Studies_on_the_Synthesis_of_Furanosteroids_I_Viridin_Models/3062557
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Alkyne oxazoles of general structure I are transformed directly to furo[2,3-b]phenol derivatives II by a sequence involving intramolecular Diels−Alder/retro-Diels−Alder reaction followed by tautomerization. Suitably functionalized phenols II undergo an intramolecular phenol−dienone−aldol condensation, generating the A,B,E-ring skeleton III characteristic of the viridin (1) class of furanosteroids.
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2006-08-31
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