metabolic data.xlsx

Using the wide range of targeted technologies and a combination of means (UPLC-MS/MS detection platform, self-built database, and multivariate statistical analysis), the addition of SBS was found to restore the levels of metabolites pathways (e.g., L-malic acid, N-acetyl-aspartic acid, N-acetyl-l-alanine, etc.) in rats, which means that the metabolic damage induced by CCl₄was alleviated.

本研究依托多样化的靶向技术体系，并结合超高效液相色谱-串联质谱（UPLC-MS/MS）检测平台、自建数据库与多变量统计分析方法，经实验验证发现，添加SBS可恢复大鼠体内多条代谢通路的代谢物水平（例如L-苹果酸、N-乙酰天冬氨酸、N-乙酰-L-丙氨酸等），这表明其能够缓解四氯化碳（CCl₄）诱导的代谢损伤。

搜集汇总

背景与挑战

背景概述

该数据集为代谢研究数据，通过UPLC-MS/MS检测平台和多元统计分析，探究SBS添加对大鼠CCl4诱导代谢损伤的缓解作用，涉及氨基酸、脂质和核酸等代谢物通路。数据集发布于figshare平台，采用CC BY 4.0许可，适用于医学生物化学领域的研究。