Disseminated Superficial Actinic Porokeratosis: Case report

Background: Disseminated superficial actinic porokeratosis is a rare disorder that presents abnormal clonal keratinization of unknown etiology. Frequently associated with UV radiation, genetic factors, and immunosuppression. It manifests clinically as solitary or multiple annular plaques surrounded by a hyperkeratotic border. Various clinical forms have been described, including disseminated superficial actinic porokeratosis, the most common subtype and represented in the following clinical case. Clinical case: A case of a 62-year-old male is presented who presents with dermatosis characterized by annular erythematosquamous plaques spread to the hands, chest and upper and lower extremities and chest with collarette scales of chronic evolution. A clinical diagnosis is made, confirmed by classic histopathology and dermoscopic findings.Conclusions. Disseminated superficial actinic porokeratosis is rare, difficult to diagnose and similar to multiple pathologies; This is why it is important to recognize them clinically and achieve timely treatment of potential malignancy that they present背景：播散性浅表性光线性汗孔角化症（disseminated superficial actinic porokeratosis）是一种病因未明的罕见克隆性角质异常性疾病。该病常与紫外线照射、遗传因素及免疫抑制状态相关。临床可表现为单发或多发的环状斑块，周边伴角化过度性边界。目前已报道多种临床亚型，其中播散性浅表性光线性汗孔角化症为最常见亚型，亦为本临床病例所呈现的类型。 临床病例：本次报告1例62岁男性患者，其皮损为慢性病程的环状红斑鳞屑性斑块，分布于手部、胸部及上下肢，皮损边缘呈领圈状鳞屑。结合典型组织病理学及皮肤镜检查结果，明确了临床诊断。 结论：播散性浅表性光线性汗孔角化症较为罕见，诊断难度较高，且需与多种皮肤病鉴别，因此临床识别该疾病并及时对其可能伴发的恶性病变开展治疗具有重要临床意义。