Diagnostic performance of recombinant proteins and their mixture using a serological panel.

Samples from asymptomatic (n = 9) or symptomatic (n = 15) L. infantum-infected dogs, sera from animals with no clinical signs of VL, and negative parasitological and serological results to Leishmania spp. antigens, and living in an endemic (n = 15) or non-endemic (n = 15) area of leishmaniasis; as well as sera from animals experimentally infected by Trypanosoma cruzi (n = 12) or Ehrlichia canis (n = 8), and sera from dogs vaccinated with Leish-Tec (n = 12); were tested in the ELISA assays. ROC curves were used to determine sensitivity, specificity and AUC (area under the curve). 95%CI: Confiance Interval. LR: Likehood Ratio. SLA: Soluble Leishmania infantum antigenic extract.