Relative risk (95% CI) of primary gallbladder cancer by WHO categories of metabolic factors (n = 575,390).

1Cut-off levels are according to WHO definition.2RRs were estimated from Cox regression models with attained age as time scale, adjusted for smoking status and age at baseline, stratified by cohort, categories of birth year, and sex.3RRs were further adjusted for BMI (except in BMI analysis).4RRs were estimated only for individuals who had fasted 8 or more hours before baseline blood sampling (n = 277,300).Abbreviations: BMI, body mass index; BP, blood pressure; CI, confidence interval; RR, relative risk.