G9a in complex with the S-isomer of RK-131902 (racemic compound rac-10a)
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G9a in complex with the S-isomer of RK-131902 (racemic compound rac-10a) Descriptor: Histone-lysine N-methyltransferase EHMT2, SINEFUNGIN, ZINC ION, ... Authors: Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Ihara, K, Shirouzu, M, Umehara, T. Deposit date: 2024-11-14 Release date: 2025-05-21 Last modified: 2025-06-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Discovery of potent substrate-type lysine methyltransferase G9a inhibitors for the treatment of sickle cell disease. Eur.J.Med.Chem., 293, 2025
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2024-11-14
