The whole genome sequencing of cloned-like chicken produced by allogeneic transplantation of induced primordial germ cells derived from somatic cells.

Generation of genetically uniformed individuals from somatic cells is an effective approach for large-scale reproduction of elite varieties and a powerful tool for restoration of endangered species. However, this technique has never been realized in avian due to their oviparous reproduction pattern. In this study, we produced cloned-like chicken by allogeneic transplantation of induced primordial germ cells (iPGCs) derived from somatic cells . Here, we conducted whole genome sequencing of cloned-like chicken and the parents Langshan Chicken and recessive white feather chicken to verify the feasibility of somatic cloning of birds.