The Cancer Genome Atlas Head-Neck Squamous Cell Carcinoma Collection (TCGA-HNSC)

The Cancer Genome Atlas Head-Neck Squamous Cell Carcinoma (TCGA-HNSC) data collection is part of a larger effort to build a research community focused on connecting cancer phenotypes to genotypes by providing clinical images matched to subjects from The Cancer Genome Atlas (TCGA). Clinical, genetic, and pathological data resides in the Genomic Data Commons (GDC) Data Portal while the radiological data is stored on The Cancer Imaging Archive (TCIA). Matched TCGA patient identifiers allow researchers to explore the TCGA/TCIA databases for correlations between tissue genotype, radiological phenotype and patient outcomes. Tissues for TCGA were collected from many sites all over the world in order to reach their accrual targets, usually around 500 specimens per cancer type. For this reason the image data sets are also extremely heterogeneous in terms of scanner modalities, manufacturers and acquisition protocols. In most cases the images were acquired as part of routine care and not as part of a controlled research study or clinical trial.

癌症基因组图谱头颈鳞状细胞癌（TCGA-HNSC）数据集是一项更大规模研究计划的组成部分，该计划旨在构建一个研究共同体，通过为来自癌症基因组图谱（The Cancer Genome Atlas, TCGA）的受试者匹配临床影像，以实现癌症表型与基因型的关联研究。临床、遗传与病理数据存储于基因组数据共享（Genomic Data Commons, GDC）门户，而放射学影像数据则存储于癌症影像档案库（The Cancer Imaging Archive, TCIA）。匹配的TCGA患者标识符可使研究人员在TCGA与TCIA数据库中开展探索，以分析组织基因型、放射学表型与患者预后之间的关联关系。为达成每种癌症类型约500份样本的招募目标，TCGA的组织样本采集自全球多个站点。正因如此，该影像数据集在扫描仪模态、设备厂商与采集协议方面均呈现极强的异质性。在多数情况下，这些影像均为常规诊疗流程中获取的资料，而非受控研究或临床试验的一部分。