Supplementary Material for: SARS-CoV-2 Lineages and Sub-Lineages Circulating Worldwide: A Dynamic Overview

<b><i>Background:</i></b> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated in Wuhan, China, in early December 2019 has rapidly widespread worldwide, becoming one of the major global public health issues of the last centuries. <b><i>Key Messages:</i></b> Over the course of the pandemic, due to the advanced whole-genome sequencing technologies, an unprecedented amount of genomes have been generated, providing invaluable insights into the ongoing evolution and epidemiology of the virus during the pandemic. Therefore, this large amount of data played an important role in the SARS-CoV-2 mitigation and control strategies. <b><i>Key Messages:</i></b> The active monitoring and characterization of the SARS-CoV-2 lineages circulating worldwide is useful for a more specific diagnosis, better care, and timely treatment. In this review, a concise characterization of all the lineages and sub-lineages circulating and co-circulating across the world has been presented in order to determine the magnitude of the SARS-CoV-2 threat and to better understand the virus genetic diversity and its dispersion dynamics.

【背景】严重急性呼吸综合征冠状病毒2（Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2）于2019年12月初起源于中国武汉，随后在全球快速蔓延，成为近百年来全球最主要的公共卫生挑战之一。
【核心要点】在新冠大流行期间，得益于先进的全基因组测序技术，科研人员已获取了海量的病毒基因组序列数据，为解析该病毒在大流行进程中的持续演化与流行病学特征提供了极为宝贵的研究视角。此类大规模数据为SARS-CoV-2的防控策略制定与实施发挥了关键作用。
【核心要点】对全球范围内流行的SARS-CoV-2谱系开展主动监测与特征解析，有助于实现更精准的诊断、更优质的临床照护以及及时的治疗干预。本综述对全球范围内流行及共流行的所有SARS-CoV-2谱系及其亚谱系进行了简明的特征梳理，旨在明确该病毒的威胁程度，并深入解析其遗传多样性与传播动力学特征。