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EGFR/MAPK signaling pathway as a target for sulforaphane-rescued heart tube malformation induced by various concentrations of PhIP exposure

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NIAID Data Ecosystem2026-03-13 收录
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we offered an insight for the first time that PhIP exposure indeed increased the risk of abnormality of early cardiogenesis, and SFN was able to rescue various concentrations of PhIP-induced abnormal heart tube formation through targeting EGFR and mediating EGFR/MAPK signaling pathway, a previously unobserved regulatory process.

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2022-03-03
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