Human bone-marrow-derived mesenchymal stem cells: control vs. cells undergoing chondrogenesis. Human bone-marrow-derived mesenchymal stem cells: control vs. cells undergoing chondrogenesis

Long non-coding RNAs profiling of human mesenchymal stem cells comparing undifferentiated HMSCs with differentiated HMSCs during chondrogenesis. The chondrogenic differentiation of HMSCs was induced by chondrogenic medium. The chondrogenic marker genes (Col2a1, Sox9 and ACAN) has been detected upregulating during this process by Q-PCR. The aim of this study is to determine key lncRNAs regulating the chondrogenic differentiation process. Overall design: Two-condition experiment, chondrogenesis vs. hMSCs. Biological replicates: each sample contains the mixture of cell sources from three parallel experiments.