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Human Arginase1 Complexed with Inhibitor Compound 24a

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Human Arginase1 Complexed with Inhibitor Compound 24a Descriptor: 3-[(2~{S},3~{R},4~{R})-4-[[(2~{S})-2-azanyl-3-methyl-butanoyl]amino]-2-carboxy-pyrrolidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, MANGANESE (II) ION Authors: Palte, R.L. Deposit date: 2020-10-30 Release date: 2021-09-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology. Acs Med.Chem.Lett., 12, 2021

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2020-10-30
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