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Regulation of Migration and Invasive Potential of Neuroblastoma Cells Mediated By MYCN miR-335 and Multiple TGF-Beta Signalling Pathway Members

ChEBI2012-04-30 更新2026-07-21 收录

母细胞瘤转移机制

TGF-β信号通路调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-3274 数据链接链接失效反馈

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资源简介：

Regulation of Migration and Invasive Potential of Neuroblastoma Cells Mediated By MYCN miR-335 and Multiple TGF-Beta Signalling Pathway Members

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创建时间：

2012-04-30

TGF-β信号通路调控

磷酸酶与肿瘤抑制

The tumor suppressor Smad4, a key mediator of the TGF-?/BMP pathways, is essential for development and tissue homeostasis. Phosphorylation of Smad4 in its linker region catalyzed by the mitogen-activa

NIAID Data Ecosystem140

RNA-seq in Hs578T cells stimulated with TGF-Ã

乳腺癌转录组学

TGF-β信号通路调控

Transforming growth factor-Ã (TGF-Ã) comprises a key component in the tumor microenvironment. It is reported that TGF-Ã can be pro-tumorigenic or anti-tumorigenic depending on various contexts. Som

NIAID Data Ecosystem100

Study of three-dimensional structure of chromatin through a 4C-seq experiment in mouse NSC shControl and shJMJD3 upon TGFβ treatment [Chst8]

染色质三维构象分析

TGF-β信号通路调控

In this study we analyzed how multiple enhancers arrange in the 3D-space to control the activation of a specific promoter. Specifically, we did a 4C-seq experiment on a ~374 Kb locus where enhancers a

NIAID Data Ecosystem70

Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic signature. Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic signature

母细胞瘤转移机制

肿瘤微环境细胞分析

To comprehensively elucidate the cellular composition of neuroblastoma bone metastatic and non-metastatic microenvironment. Bone marrow tissue from neuroblastoma patients were obtained from surgical r

NIAID Data Ecosystem120

Galunisertib (LY2157299), a transforming growth factor-β receptor I kinase inhibitor, attenuates acute pancreatitis in rats

急性胰腺炎

TGF-β信号通路调控

Galunisertib (LY2157299), a selective ATP-mimetic inhibitor of TGF-β receptor I (TGF-βRI), is the only known TGF-β pathway inhibitor. In the present study, we investigated the effect of galunisertib o

NIAID Data Ecosystem80

Regulation of Migration and Invasive Potential of Neuroblastoma Cells Mediated By MYCN miR-335 and Multiple TGF-Beta Signalling Pathway Members

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