Outcomes and predictors of in-hospital mortality among patients admitted to the intensive care or step-down unit after a rapid response team activation: a retrospective cohort study

Introduction: It has been demonstrated that the implementation of rapid response teams (RRT) may improve clinical outcomes. Nevertheless, predictors of mortality among patients admitted to the intensive care unit (ICU) or to the step-down unit (SDU) after a RRT activation are not fully understood.
Objective: To describe clinical characteristics, resource use, main outcomes, and to address predictors of in-hospital mortality among patients admitted to the ICU/SDU after RRT activation.
Methods: Retrospective single-center cohort study conducted in a medical-surgical ICU/SDU located in a private quaternary care hospital. Adult patients admitted to the ICU or SDU between 2012 and 2020 were compared according to in-hospital mortality. A multivariate logistic regression analysis was performed to identify independent predictors of in-hospital mortality.
Results: Among the 3841 patients included in this analysis [3165 (82.4%) survivors and 676 (17.6%) non-survivors], 1972 (51.3%) were admitted ..., Data Collection and Study Variables
All study data were retrieved from an institutional yellow code data bank, and from Epimed Monitor System® (Epimed Solutions, Rio de Janeiro, Brazil) (19), which are structured electronic case report forms where patients’ data are prospectively entered by trained hospital case managers. All data were extracted by an independent research assistant who did not participate in this study. All data were fully anonymized before being made available to the researchers. The data were accessed and extracted on 28/06/2021.
The collected variables included demographics, comorbidities, Simplified Acute Physiology Score (SAPS 3 score) (20), Sequential Organ Failure Assessment (SOFA) score (21) at ICU/SDU admission, Charlson Comorbidity Index (CCI) (22), Modified Frailty Index (MFI) (23), reason for ICU or SDU admission, the MEWS (10) at the moment of RRT activation, reason for RRT activation, patient’s location before unit admission, the time elapsed between patien..., , # Outcomes and predictors of in-hospital mortality among patients admitted to the intensive care or step-down unit after a rapid response team activation: a retrospective cohort study

[https://doi.org/10.5061/dryad.m37pvmdc8](https://doi.org/10.5061/dryad.m37pvmdc8)

## Description of the data and file structure

#### SPSS data bank

The de-identified data (data_bank5.sav) presented here has been used for the analyses reported in the manuscript \"Outcomes and predictors of in-hospital mortality among patients admitted to the intensive care or step-down unit after a rapid response team activation: a retrospective cohort study.\" This SPSS file contains baseline characteristics, Rapid Response Team (RRT) activation details, and outcome data for patients admitted to the Intensive Care Unit (ICU) or Stepdown Unit (SDU) after a rapid response team activation. To maintain data anonymization, time-related variables (namely, length of stay before unit admission, unit length, and hospital length...

引言：已有研究证实，快速反应团队（Rapid Response Team, RRT）的部署可改善临床结局。然而，针对快速反应团队激活后收治于重症监护病房（Intensive Care Unit, ICU）或阶梯病房（Step-down Unit, SDU）的患者，其院内死亡的预测因子尚未完全明确。

研究目标：描述快速反应团队激活后收治于ICU/SDU患者的临床特征、资源利用情况及主要结局，并探讨其院内死亡的预测因子。

方法：本研究为回顾性单中心队列研究，开展于巴西里约热内卢某私立四级诊疗医院的内科-外科ICU/SDU。研究纳入2012年至2020年间收治于ICU或SDU的成年患者，根据院内存活状态进行分组比较。采用多因素logistic回归分析，识别院内死亡的独立预测因子。

结果：本研究共纳入3841例患者[3165例（82.4%）存活者，676例（17.6%）非存活者]，其中1972例（51.3%）患者为……

数据收集与研究变量
所有研究数据均提取自机构黄色代码数据库，以及巴西里约热内卢Epimed Solutions公司开发的Epimed Monitor System®（参考文献19）；该系统为结构化电子病例报告表，由经过培训的医院病例管理人员前瞻性录入患者数据。所有数据由未参与本研究的独立研究助理提取，且在提供给研究人员前已完成完全匿名化处理。数据获取与提取工作于2021年6月28日完成。

本次采集的变量包括人口学特征、合并症情况、ICU/SDU入院时的简化急性生理学评分3（Simplified Acute Physiology Score 3, SAPS 3）、序贯器官衰竭评估（Sequential Organ Failure Assessment, SOFA）评分、Charlson合并症指数（Charlson Comorbidity Index, CCI）、改良虚弱指数（Modified Frailty Index, MFI）、ICU/SDU入院指征、快速反应团队激活时的修正早期预警评分（Modified Early Warning Score, MEWS）、快速反应团队激活原因、入院科室前的患者所在位置、患者入院前的耗时间隔……

# 快速反应团队激活后收治于重症监护病房或阶梯病房患者的院内死亡结局与预测因子：一项回顾性队列研究

[https://doi.org/10.5061/dryad.m37pvmdc8](https://doi.org/10.5061/dryad.m37pvmdc8)

## 数据与文件结构说明
#### SPSS数据库
本研究公开的去标识化数据文件data_bank5.sav，已用于本研究论文《快速反应团队激活后收治于重症监护病房或阶梯病房患者的院内死亡结局与预测因子：一项回顾性队列研究》的数据分析。该SPSS文件包含快速反应团队激活后收治于ICU或SDU患者的基线特征、快速反应团队激活详情及结局数据。为保障数据匿名性，部分时间相关变量（即入院前住院时长、科室停留时长及医院总住院时长……