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Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration: part II

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=6726ba7bf5e494491bd5255b75dfdbf7
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We identified that microRNA-150 is upregulated in aged macrophages of diverse origins and therefore may mechanistically skew them towards a disease-promoting phenotype. The purpose of this experiment was to identify how the murine transcriptome changes with microRNA-150 overexpression.

我们发现,微RNA-150(microRNA-150)在多种来源的衰老巨噬细胞中呈现上调表达状态,因此可从机制层面促使这类巨噬细胞向促疾病表型偏移。本实验旨在探究小鼠转录组在微RNA-150过表达条件下的变化情况。
提供机构:
Washington University School of Medicine
创建时间:
2022-02-20
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