five

Isabella Gavazzi (2011) CIL:39001, sensory neuron. CIL. Dataset

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Sensory neuron from an adult dorsal root ganglion immunostained for Growth Associated Protein (GAP43) shown in red. Neurites are growing in between stripes containing the EphrinA5 protein (green). When the cell processes come into contact with this protein they are repelled and therefore grow along between the stripes. The effects of the Ephrin molecules are mediated through a family of tyrosine kinase receptors and are important in providing repulsive signals during the development of the nervous system

成年背根神经节中感觉神经元对生长相关蛋白(GAP43)进行免疫染色,结果显示为红色。神经突在含有EphrinA5蛋白(绿色)的条纹之间生长。当细胞处理过程与该蛋白接触时,受到排斥并因此沿条纹之间生长。Ephrin分子效应通过酪氨酸激酶受体家族介导,对于神经系统发育过程中提供排斥信号具有重要意义。
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