Traf2

ENCODES a protein that exhibits mitogen-activated protein kinase kinase kinase binding; protein kinase binding; protein-containing complex binding; INVOLVED IN negative regulation of glial cell apoptotic process; positive regulation of NF-kappaB transcription factor activity; tumor necrosis factor-mediated signaling pathway; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; ceramide signaling pathway; ASSOCIATED WITH Transplant Rejection; Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); FOUND IN cell cortex; protein-containing complex; CD40 receptor complex (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol; 1H-pyrazole

编码一种表现出丝裂原激活蛋白激酶激酶激酶结合、蛋白激酶结合、蛋白复合物结合特性的蛋白质；参与胶质细胞凋亡过程的负调节、NF-κB转录因子活性的正调节、肿瘤坏死因子介导的信号通路；参与肿瘤坏死因子介导的信号通路、c-Jun N-端激酶MAPK信号通路、鞘脂信号通路；与移植排斥、Adams-Oliver综合征5（同源）、常染色体显性智力发育障碍8（同源）相关；存在于细胞皮质、蛋白复合物、CD40受体复合物（同源）中；与1,1,1-三氯-2-(邻氯苯基)-2-(对氯苯基)乙烷、17β-雌二醇、1H-吡唑等相互作用。