Mapping open chromatin regions has emerged as a widely used tool for identifying active regulatory elements in eukaryotes. However, existing approaches, limited by reliance on DNA fragmentation and sh

NIAID Data Ecosystem70

A long-read RNA-seq approach to identify novel transcripts of very large genes

长读长测序

基因转录组学

RNA-seq is widely used for studying gene expression, but commonly used sequencing platforms produce short reads that only span up to two exon-junctions per read. This makes it difficult to accurately

NIAID Data Ecosystem50

Table_3_Long Read Single-Molecule Real-Time Sequencing Elucidates Transcriptome-Wide Heterogeneity and Complexity in Esophageal Squamous Cells.xlsx

食管鳞状细胞癌转录组学

长读长测序

Esophageal squamous cell carcinoma is a leading cause of cancer death. Mapping the transcriptional landscapes such as isoforms, fusion transcripts, as well as long noncoding RNAs have played a central

NIAID Data Ecosystem80

be0d489f-6483-4d9f-a9cb-4addd1a7a9aa - samples

长读长测序

人类单核细胞基因组

PacBio continuous long read (CLR) sequencing data for individual HV31 generated on PacBio Sequel II instrument, using DNA from CD14+ monocytes, to a sequencing depth of ~35ÃƒÂ—. Sequencing was perform

NIAID Data Ecosystem70

Xdrop - Oxford Nanopore long read seqeuncing of HepG2 genetic modified clones

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