Proteomics Characterization of Longitudinal CSF from ALS Fast and Slow Progressors
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https://www.omicsdi.org/dataset/pride/PXD035026
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Each CSF sample was concentrated and added to a multiple affinity removal spin cartridge .The eluates were subjected to a buffer exchange and proteins were reduced using DTT and alkylated using iodoacetamide. Digestions were performed using trypsin. CSF from patients with amyotrophic lateral sclerosis (ALS) was characterized via LC-MS/MS. Biomarkers were identified to differentiate fast and slow progressors.
创建时间：
2024-01-26
