MCA2.0 DGE Data

MCA2.0_Fig1_adata.h5ad: contains both raw count and normalized datasets for 520,801 cells in MCDA, which can be processed into the python environment with SCANPY directly. dge_raw_data.zip: contains separate raw count matrices for ten mouse tissues (brain, heart, lung, liver, kidney, stomach, intestine, pancreas, testis, and uterus) at seven life stages (E10.5Day, E12.5Day, E14.5Day, P0, P10, P21, and Adult). MCA2.0_cell_info.csv: contains the cell annotations for 520801 cells in MCDA, including UMAP coordinates, development stages, tissue origins, lineages, and cell-type annotations in both 95 clusters and tissues per stage.

MCA2.0_Fig1_adata.h5ad：包含小鼠细胞图谱数据集（Mouse Cell Atlas Dataset，简称MCDA）中520,801个细胞的原始计数与标准化数据集，可直接通过SCANPY库导入Python环境进行处理。
dge_raw_data.zip：包含10种小鼠组织（脑、心脏、肺、肝脏、肾脏、胃、肠道、胰腺、睾丸及子宫）在7个发育阶段（E10.5Day、E12.5Day、E14.5Day、P0、P10、P21及成年期）的独立原始计数矩阵。
MCA2.0_cell_info.csv：包含MCDA中520,801个细胞的细胞注释信息，涵盖UMAP (Uniform Manifold Approximation and Projection) 坐标、发育阶段、组织来源、细胞谱系，以及95个聚类和各阶段组织对应的细胞类型注释。

搜集汇总

背景与挑战

背景概述

MCA2.0 DGE Data是一个包含520,801个小鼠细胞的多组织单细胞转录组数据集，涵盖十个组织和七个发育阶段，提供原始计数、标准化数据和详细细胞注释信息，适用于生物信息学和发育生物学研究。