Additional file 1 of Rationale and development of an e-health application to deliver patient-centered care during treatment for recently diagnosed multiple myeloma patients: pilot study of the MM E-coach

Additional file 1: Fig. S1. Mockup example of a medication overview for patients of one of the treatment schedules (Rd; lenalidomide/dexamethasone and co-medication). The text boxes next to the date display time by day or week; The columns represent medication type, medication dose, medication time and additional instructions. Fig. S2. Medication overview of one of the treatment schedules (KRd; carfilzomib/lenalidomide/dexamethasone and co-medication). The menu to the left is identical to figure 3; the columns to the right are comparable to figure S1. Fig. S3. Medication registration page. The menu to the left is comparable to figure 3. Each line represents one medication with information, for example acetylsalicylzuur translates to acetylsalicylic acid and the bold text to ‘dosing’, ‘aim’, ‘brand types’, ‘time of preference’, ‘side effects’, ‘additional remarks’. Fig. S4. Outpatient visit preparation questionnaire (not showing blank space). The menu to the left is comparable to figure 3 and marks ‘Outpatient clinic preparation’. The text contains an introduction asking patients what complaints or side effects they experience at that give moment and states that a patient can tick as many boxes as apply to that moment. Then every line represents one complaint, for example ‘Braken’ means ‘Vomiting’. Fig. S5. Periodic assessment, one question example. The menu to the left is comparable to figure 3 and marks ‘Periodic check’. The question translates to ‘How would you judge your health during the last week?’ and the answers range from ‘very bad’ to ‘excellent’. Fig. S6. Ad hoc complaint form completed, followed by advice. This displays the healthcare provide account, zooming in on one specific part of a questionnaire that was filled out by a patient. The second yellow alert line states the question ‘Do you experience vomiting for more than 24 hours’, as a follow-up question when the patient has ticked ‘vomiting’ in the list in figure S4. At the most right it states that the patient has answered ‘Nee’ (No). Fig. S7. Healthcare provider alert list, including one active alert. This displays the healthcare provider account, highlighting the ‘Interventielijst’ (List of interventions) that indicates a red alert for a given patient at a given time.

附加文件1：图S1 某治疗方案（Rd：来那度胺/地塞米松及合并用药）患者用药概览的示例样机。日期旁的文本框以日或周为单位展示时间；列项分别对应用药类型、用药剂量、用药时间及附加说明。
图S2 某治疗方案（KRd：卡非佐米/来那度胺/地塞米松及合并用药）的用药概览。左侧菜单与图3一致，右侧列项与图S1类似。
图S3 用药登记页面。左侧菜单与图3类似，每行代表一条含完整信息的用药记录，例如乙酰水杨酸（acetylsalicylic acid，原文为acetylsalicylzuur），粗体文本分别对应“给药方案”“用药目标”“品牌剂型”“偏好用药时间”“不良反应”“附加备注”。
图S4 门诊就诊准备调查问卷（未展示空白区域）。左侧菜单与图3类似，标注“门诊准备”。文本开篇为引导语，询问患者当前出现的不适或不良反应，并说明患者可勾选当前适用的所有选项。随后每行代表一种不适症状，例如“Braken”对应“呕吐”。
图S5 周期性评估示例题目。左侧菜单与图3类似，标注“定期检查”。题目翻译为“你如何评价过去一周的健康状况？”，答案选项范围从“极差”至“极佳”。
图S6 已填写的临时不适表单及后续建议。该页面展示医疗服务方账号，聚焦于患者已填写的某一问卷条目。第二条黄色警示行的问题为“你是否已呕吐超过24小时”，是患者在图S4的列表中勾选“呕吐”后的跟进问题。页面最右侧标注患者已回答“Nee”（否）。
图S7 含1条激活警示的医疗服务方警示列表。该页面展示医疗服务方账号，高亮显示“干预清单（Interventielijst）”，其代表特定患者在特定时间的红色警示。