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A Water-Soluble, Small Molecular Fluorescent Sensor with Femtomolar Sensitivity for Zinc Ion

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NIAID Data Ecosystem2026-03-06 收录
下载链接:
https://figshare.com/articles/dataset/A_Water_Soluble_Small_Molecular_Fluorescent_Sensor_with_Femtomolar_Sensitivity_for_Zinc_Ion/2973220
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A water-soluble fluorescent sensor, 1, based on the quinoline platform, demonstrates femtomolar sensitivity for zinc ion with a 14-fold enhanced quantum yield upon chelation to zinc ion and also exhibits high selectivity to zinc ion over other physiological relevant divalent metals in the presence of EDTA. X-ray crystal structure of zinc complex reveals that an acetic carboxylic group participates in coordination, which significantly enhances the affinity of 1 for zinc ion.
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2016-06-03
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